Cytokines and immuno-endocrine factors in recurrent miscarriage.
نویسندگان
چکیده
Recurrent miscarriage remains an enigma. The main aetiologies are endocrinological, immunological and unexplained. With the growth in molecular biology, it is now possible to look at the effect of these aetiologies in more detail, allowing greater understanding of the underlying pathogenesis.
منابع مشابه
I-43: Investigation and Treatment of Coupleswith Recurrent Miscarriage in Royan
Recurrent abortion is classically defined as three or more consecutive pregnancy losses, although recently more than two pregnancy losses also considered as recurrent abortions. This condition affects approximately 1% of couples at reproductive age. Recurrent pregnancy loss has been attributed to anatomic uterine pathologies, genetic defects, endocrine disorders, immunologic factors, prothrombo...
متن کاملDepression as a potential causal factor in subsequent miscarriage in recurrent spontaneous aborters.
BACKGROUND Unexplained miscarriage is speculated to be due to a Th1/Th2 cytokine imbalance at the feto-maternal interface and immunological functions are known to be under the influence of various psychological factors. Indeed, the psycho-neuro-immuno-endocrine network has been proposed to contribute to miscarriage. To assess whether psychological disorders might induce spontaneous abortion we ...
متن کاملI-24: New Molecular Aspects in Recurrent Pregnancy Loss
Background Recurrent pregnancy loss (RPL) is usually defined as three or more consecutive pregnancy losses before 20th gestational week. Many etiological factors have been considered as cause of RPL including genetic factors, uterine anatomical defects, endocrine abnormalities, thrombotic and immunologic factors. Nevertheless, the cause of RPL remains unknown in around half of the patients desp...
متن کاملRecurrent miscarriage
Miscarriage is one of the most common complications of pregnancy. Fifteen percent of clinically recognized pregnancies end in miscarriage. The major cause of spontaneous miscarriage is genetic or developmental abnormalities of the foetus. Recurrent miscarriage occurs in 3% of the population and has been associated with thrombophillias, infections and endocrine, anatomical and immune factors. Tr...
متن کاملPsychosocial factors regulating natural-killer cell activity in recurrent spontaneous abortions.
PROBLEM The preconceptional natural-killer cell (NK) activity predicts subsequent miscarriage among women with unexplained recurrent spontaneous abortion (RSA). Psycho-neuro-immuno-endocrine network has recently been proposed as a mechanism for abortions. We therefore examined which psychosocial factors influenced the NK activity among women with RSA. METHOD OF STUDY We measured the preconcep...
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عنوان ژورنال:
- Human reproduction update
دوره 2 6 شماره
صفحات -
تاریخ انتشار 1996